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ey0018.2-20 | Maternal Obesity and Long-term Infant Consequences | ESPEYB18

2.20. Maternal obesity influences placental nutrient transport, inflammatory status, and morphology in human term placenta

P Nogues , E Dos Santos , A Couturier-Tarrade , P Berveiller , L Arnould , E Lamy , S Grassin-Delyle , F Vialard , MN Dieudonne

J Clin Endocrinol Metab. 2021 Mar 25;106(4):e1880e1896. doi: 10.1210/clinem/dgaa660. PMID: 32936881.By studying placentas from normal weight mothers and obese (non-diabetic) mothers, the authors found that maternal obesity was associated with lower expression of nutrient transporters (such as for glucose and amino acids), surprisingly fewer immune cells, and compromised endocrine func...

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ey0018.12-9 | Metabolic Syndrome | ESPEYB18

12.9. Sugar-Induced obesity and insulin resistance are uncoupled from shortened survival in drosophila

E Van Dam , LAG van Leeuwen , E Dos Santos , J James , L Best , C Lennicke , AJ Vincent , G Marinos , A Foley , M Buricova , JB Mokochinski , HB Kramer , W Lieb , M Laudes , A Franke , C Kaleta , HM Cocheme

Cell Metab. 2020; 31(4):710725.e7. doi: 10.1016/j.cmet.2020.02.016. PMID: 32197072.In brief: High-sugar diets cause thirst, obesity and metabolic dysregulation, leading to insulin resistance, the MetS, T2DM and shortened lifespan. This study shows that high sugar diets induce dehydration in adult Drosophila. Water supplementation fully rescued the shortened lifespan, but ...

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ESPE Yearbook of Paediatric Endocrinology

2.20. Maternal obesity influences placental nutrient transport, inflammatory status, and morphology in human term placenta

12.9. Sugar-Induced obesity and insulin resistance are uncoupled from shortened survival in drosophila

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